Menstruation always go not clean is most often seen in irregular menstruation, submucosal fibroids, endometrial thickening and other diseases, need to be targeted treatment. If irregular menstruation, can be under the guidance of the doctor to take menstrual regulation drugs, such as progesterone capsules. Submucosal fibroids require timely surgical treatment, such as total hysterectomy. Thickening of the uterine lining requires timely scraping treatment. 1. Irregular menstruation: mainly due to endocrine disorders, can be diagnosed through the sex hormone six test, and then the doctor’s guidance to take menstrual regulation drugs, such as progesterone capsules. 2. Submucosal fibroids: as the tumor growth will invade the endometrium, it will also cause the menstruation to be always unclean, which needs timely surgical treatment, such as sub-total uterine excision and total uterine excision. 3. Thickening of uterine lining: as the thickness of uterine lining exceeds the normal range, it will also cause unclean menstruation, which needs timely scraping treatment. In addition, menstruation may also be related to other factors, such as taking certain drugs or blood diseases, etc. It is recommended that the patient go to the gynecology department of the hospital in time for examination, to clarify the cause of the disease and then follow the doctor’s instructions for treatment, in order to prevent further aggravation of the condition.