The pimples under the lips are painful due to folliculitis under the lips, folliculitis is a common bacterial infection bacterial skin disease in dermatology clinics, the main causative organism is Staphylococcus aureus, resulting in superficial inflammation of the hair follicle mouth, the clinical manifestation is mainly inflammatory papules, which develop into small pustules with time, surrounded by redness and pressure pain to touch. When the number of rashes is small and the pain is tolerable, it is recommended to use anti-inflammatory ointment topical rubbing treatment, you can use Bactroban ointment, compound polymyxin B ointment, fusidic acid ointment, erythromycin ointment, etc. can be used. If the area is larger, more pustules, more inflammatory papules, more obvious pain, etc., it is recommended that patients can take oral anti-inflammatory drugs, such as cephalosporin, penicillin and other symptomatic support treatment when using topical antibiotic ointment.