If Mycoplasma pneumoniae antibody IgM1:300, combined with relevant clinical symptoms, the presence of Mycoplasma pneumoniae pneumoniae infection is considered, and anti-infection and symptomatic treatment are needed. There are two types of Mycoplasma pneumoniae antibodies, one is IgM and the other is IgG. Positive IgG titer indicates that one has been infected with Mycoplasma pneumoniae, and cannot be used as the basis for this diagnosis; positive IgM antibody can be used as an indicator of recent infection. Mycoplasma pneumonia, an atypical pneumonia, can manifest as interstitial pneumonia, which will present with dry cough and fever, and most patients have a good prognosis, while a small number of patients can develop severe pneumonia. Clinical treatment, the use of macrolides, such as azithromycin, roxithromycin, etc., symptomatic use of antipyretic, expectorant drugs, commonly used antipyretic drugs such as ibuprofen, acetaminophen, expectorant drugs such as bromohexine, aminoglutethimide, acetylcysteine and so on. If Mycoplasma pneumoniae antibody IgM1:300 is present, it is recommended to consult a doctor for early treatment.