What does the absence of genetic mutations in lung adenocarcinoma mean

Lung adenocarcinoma without gene mutation means that no known gene mutation has been found and targeted therapy cannot be performed.
Lung adenocarcinoma without gene mutation is one of the results of genetic examination, which means that no known mutated gene has been found, indicating that the patient is not suitable for targeted therapy, and can only be treated with surgery, radiotherapy, chemotherapy, immunotherapy and other treatments.
Lung adenocarcinoma patients without gene mutation should mainly be treated with surgical resection in early stage, while patients in middle and late stage who cannot be operated can be treated with comprehensive programs such as radiotherapy, chemotherapy and immunotherapy, so as to improve their quality of life and prolong their survival cycle.