Taking Radix Rehmanniae Pill with Conjugated Zi may raise blood pressure. Radix Rehmanniae Pill consists of Radix Rehmanniae Praeparata, Radix Codonopsis Pilosulae, Rhizoma Atractylodis Macrocephalae, Radix et Rhizoma Glycyrrhizae Praeparatae and Radix et Rhizoma Glycyrrhizae. It has the effect of warming the middle and strengthening the spleen. It is used for cold pain in the epigastrium (feeling cold pain in the stomach and abdomen), cold limbs and loose stools (thin and unformed feces). The adverse reactions and contraindications of Radix Rehmanniae Pill are not clear, pregnant women should be cautious, and should not be used in acute gastroenteritis, diarrhea with loose stools and burning anus. This product contains epiphyllum, after taking the drug, if there is an increase in blood pressure, headache, palpitations (rapid heartbeat, often accompanied by panic) and other symptoms, the drug should be immediately discontinued, seek medical attention. Hypertensive patients taking this medicine to treat related diseases, need to be taken under the guidance of a traditional Chinese medicine practitioner to identify the evidence, do not take blindly, in order to avoid damage to the body and aggravate the condition.