Girls sixteen years old long acne is a normal phenomenon, such as suffering from too much acne, you can choose to adjust the regularity of life, medication, physical and chemical treatment and so on. 1. Life rules: to change the bad eating habits, eat less high sugar, greasy, spicy stimulating food. Eat more fresh fruits and vegetables, work and rest regularly, avoid staying up late. 2. Medication: topical retinoids (adapalene gel, tazarotene gel), benzoyl peroxide, azelaic acid, antibiotics (fusidic acid cream, mupirocin ointment) can be used. If the condition is more serious, you can also take oral isotretinoin capsules, doxycycline tablets and other drugs. 3. Physical and chemical treatments: There are treatments such as laser and chemical peeling, which are commonly used as alternative treatments for acne. When acne affects your life and body and mind too much, you should go to regular hospital for treatment. The above medicines should be used according to the doctor’s prescription.