With the widespread use of high-frequency ultrasound, more and more microscopic breast lesions are being detected, and how to accurately and easily treat these non-palpable breast lesions (NPBL) of unknown nature has become a problem that breast surgeons must solve. The problem has become a must for breast surgeons. Open surgical biopsy is still the conventional means of confirming the diagnosis of breast lesions, but it is difficult to locate small lesions that are not palpable, and to ensure that the lesions are removed, it is often necessary to remove more normal breast tissue, or even a large section of normal glandular tissue, and it is not clear whether there is a residual lesion. Although hollow-core needle biopsy of non-felt breast lesions is more reliable than fine needle aspiration cytology, it is sometimes not easy to obtain sufficient specimens to distinguish in situ breast cancer from invasive cancer. Ultrasound-guided hollow-core needle aspiration can improve the diagnostic rate of these methods, but cannot completely remove the lesion. The vacuum-assisted breast biopsy system under ultrasound guidance can solve these problems, i.e., it can accurately remove the non-palpable lump (NPBL) under ultrasound guidance, check whether there is any residue after surgery, obtain enough specimens to distinguish in situ or invasive cancer, and perform immunohistochemical examination to further type the tumor; if necessary, the lesion can be completely removed. In 2006, the State Food and Drug Administration of China approved this technology for clinical use in China. The vacuum-assisted breast biopsy system consists of a rotary cutter (biopsy needle) and a vacuum suction pump. The biopsy needle has a transmission device, which can send the cut specimen out of the body through the movement of the inner sleeve needle without withdrawing the outer sleeve needle, and then repeat cutting, so that all cutting can be completed with one puncture and positioning.