The presence of intravascular cancer thrombus on the pathology report is usually diagnosed in the pathology report after surgical resection, and this condition may be one of the high-risk factors, which requires chemotherapy, endocrine therapy and targeted therapy. For example, gastric cancer patients with intravascular cancer embolus should be given systemic chemotherapy, and the applied regimen includes oxaliplatin plus tiglio. Breast cancer patients should be given anthracycline chemotherapeutic drugs, as well as cyclophosphamide and paclitaxel chemotherapeutic drugs, etc., and endocrine therapy should be applied according to the endocrine condition. In some patients, targeted therapy may also be needed, and the choice of drugs varies depending on the site of treatment, so it is recommended to follow the doctor’s instructions. However, vascular tumor embolus only suggests the risk of vascular metastasis, it does not mean that metastasis has definitely occurred, patients do not need to worry too much, it is recommended to follow the doctor’s instructions for standardized treatment.