Ankylosis generally refers to ankylosing spondylitis, which is asymptomatic and still requires treatment to slow disease progression and avoid long-term joint deformities. At the same time taking into account non-pharmacological and pharmacological treatment. Ankylosing spondylitis is a chronic inflammatory disease, the cause of which is related to genetics, infection, immune inflammatory factors and other factors. Early on, patients may experience pain and discomfort in the lumbosacral region, which can be alleviated with activity. If the patient does not experience discomfort, treatment is still needed, taking into account both non-pharmacological and pharmacological treatments. Non-pharmacological treatments include correcting poor sitting and standing postures, cultivating good living habits, and strengthening exercise as appropriate. Maintain a positive and optimistic mindset and avoid overwork. Diet should be based on light and easy-to-digest food, avoid overeating, and eat more fiber-rich food to prevent constipation. Medication includes the use of immunosuppressants such as Liuzosulfapyridine to slow down the progression of the disease. Patients with ankylosing spondylitis are advised to go to a regular hospital in time and take relevant treatment measures under the guidance of a doctor, and to follow the doctor’s instructions for regular review during the treatment period, and do not use medication on their own.