When you wake up in the morning, you need to rule out whether the eye is swollen unilaterally or bilaterally. If it is unilateral eye swelling, you need to rule out inflammation, mosquito bites, trauma or some allergies caused by eye swelling, as well as eye lesions. If bilateral eyelid edema is present, bilateral eye problems or allergies need to be ruled out, and if localized lesions are ruled out, systemic diseases need to be considered, most commonly cardiac lesions and renal lesions. Kidney lesions often have bilateral eyelid edema and large amounts of foam in the morning urine that does not go away. Cardiac lesions can present with arrhythmias, palpitations after activity, and an inability to lie flat at night. Of course bilateral eyelid edema caused by other systems also exists and needs to be analyzed on a case-by-case basis. There is a situation that drinking a lot of water before going to bed and not urinating at night, can appear bilateral eyelid edema, or night rest is not good bilateral eyelid edema, which need to be analyzed on a case-by-case basis so as not to delay the diagnosis of the disease, and need to be carefully differential diagnosis.