Sore throat can be seen in acute pharyngitis, acute tonsillitis, acute laryngitis, etc. It should be treated according to the cause of the disease, including medication, nebulizer treatment, lifestyle adjustment, etc. Acute pharyngitis: it is caused by viral infection, bacterial infection and stimulation of physical and chemical factors. If the systemic symptoms are severe, the treatment should first of all be bed rest, drink more water and enter fluid food, choose antiviral drugs, such as ribavirin, etc.; antibacterial drugs, such as amoxicillin, cefuroxime, roxithromycin, etc.; local treatment application of compound borax solution gargling, iodine tablets containing chemotherapy and other treatments. Acute tonsillitis: if there is a bacterial infection, antibiotics need to be applied, preferred penicillin, or the application of cephalosporins and macrolides antibiotics, such as cefuroxime, azithromycin and so on. Combined application of compound borax solution, iodine-containing tablets, etc. to relieve local discomfort. Acute laryngitis: commonly used drugs include antibiotics (such as penicillin, cephalosporin), glucocorticosteroids (such as prednisone, dexamethasone) and so on. To reduce talking, eat less spicy and irritating food. Local nebulization treatment, applying inhalation budesonide suspension to reduce vocal cord edema. Patients with sore throat are advised to consult the hospital, and after the diagnosis is clear, follow the doctor’s instructions for medication and treatment.