Diarrhea, low fever, body weakness and pain, may be gastrointestinal cold, bacterial dysentery or acute gastroenteritis, etc., should cooperate with the doctor to improve the blood, stool routine, C-reactive protein and other tests, a clear diagnosis, to take the symptomatic drug treatment, such as oral medication, intravenous drip drugs. 1. Gastrointestinal colds: If gastrointestinal colds lead to diarrhea, low-grade fever, weakness and soreness, you can take antidiarrheal drugs, antipyretic and painkillers, antibiotics and anti-inflammatory drugs, such as montelukast, houliqiangzhengqi water, ibuprofen, ciprofloxacin, levofloxacin, and so on. If the diarrhea is more serious, you can consider intravenous drugs, infusion treatment. 2. Bacterial dysentery: If the bacterial dysentery caused by diarrhea and low-grade fever weakness and soreness, mainly related to the lack of attention to diet and hygiene, you can take antibiotic anti-inflammatory drugs, antidiarrheal drugs, antipyretic drugs, antispasmodics and other medications, such as levofloxacin, ceftriaxone, montelukast, ibuprofen, atropine and so on. 3. Acute gastroenteritis: If acute gastroenteritis leads to diarrhea and low fever weakness and soreness, you can take ibuprofen, lactobacillus tablets, montelukast, etc. for treatment, and if necessary, intravenous hydration therapy. If the diarrhea low fever weakness and soreness, it is recommended to go to the regular hospital as soon as possible, and under the guidance of a professional doctor standardized medication.