The difference between Cephalosporin and Amoxicillin Clavulanate Potassium is different kinds, antibacterial spectrum, and adverse reactions. 1. Different types: Cephalosporin is a cephalosporin antibiotic, and Amoxicillin Clavulanate Potassium is a penicillin antibiotic. 2. Different antibacterial spectrum: clinically cephalosporin is divided into five generations, different types of cephalosporin have different degrees of antibacterial activity against gram-positive bacteria and gram-negative bacteria. Clinically, they are commonly used in the treatment of serious infections caused by drug-resistant S. aureus and gram-negative bacteria, such as lung infections, urinary tract infections, sepsis, meningitis, endocarditis and so on. Amoxicillin Clavulanate Potassium is used for lower respiratory tract infections, otitis media, sinusitis caused by enzyme-producing Haemophilus influenzae and Catamoeba; urinary tract infections and soft tissue skin infections caused by enzyme-producing Staphylococcus aureus and and enzyme-producing Enterobacteriaceae, etc.; mild to moderate infections caused by Enterococcus faecalis; and above mentioned infectious diseases caused by non-enzyme-producing strains. 3. Adverse reactions are different: the common adverse reactions of cephalosporin are allergic reactions, such as rash, urticaria, drug rash, eosinophilic leukocytosis and so on. Amoxicillin Clavulanate Potassium common adverse reactions for gastrointestinal reactions, but also cause skin rash, anaphylaxis, drug fever, asthma, serum aminotransferase elevation, eosinophilia, leukopenia, Candida or drug-resistant bacterial secondary infections and so on. If you need to use Cephalosporin and Amoxicillin Clavulanate Potassium, consult a medical professional and use the medication as prescribed.