Recently, we successfully completed another case of pancreatic body caudal cystadenoma with laparoscopic pancreatic body caudal resection plus splenectomy. We would like to report to you some experiences and lessons learned. The patient was a 53-year-old female who was admitted to the hospital with upper abdominal discomfort for 2 months, and CT showed “a large cystic solid occupancy in the body of the pancreas with no surrounding lymph node enlargement. She was considered to be benign and decided to undergo laparoscopic surgery. During the operation, we saw that the tumor was large and the splenic artery and vein were close together, so we decided to perform splenectomy in parallel. The operation lasted 5 and a half hours, with little bleeding, and the patient recovered satisfactorily after the operation without complications. At present, laparoscopic surgery has become a representative of minimally invasive surgery, and laparoscopic pancreatic body caudal resection with splenectomy has become a classic procedure for benign tumors in the body caudal part of the pancreas, with obvious advantages of less trauma and faster recovery. However, it must be done by a surgeon with certain experience in laparoscopic operation, and the operation must be done carefully and with delicate movements. In addition, the spleen can be preserved for benign or benign-malignant junctional tumors of the body tail of the pancreas, low-grade malignant lesions and chronic pancreatitis. The significance of this is that it can prevent sepsis and platelet elevation due to splenectomy and preserve the immune function of the tumor. In this case, the surgical occupancy was large and it was somewhat difficult to preserve the spleen, so the spleen was removed together for safety. The following are some CT and some surgical pictures, we hope to correct them.