Hormones are one of the most controversial of all the forms of Strokes, and the first case of Strokes treated with hormones appeared in 1949, when the patient was miraculously relieved of pain and was able to get up and walk. It was thought that a drug had been found to treat the disease. However, a series of subsequent clinical studies determined that hormones were not a good treatment for the disease. Because it is very difficult to reduce and stop hormone therapy after a patient receives it, long-term use of hormone therapy has more side effects than itself. However, because hormones have a very strong anti-inflammatory and pain-relieving effect on wind-like guan, both the patient and the patient cannot live without it. Gradually, patients become dependent on hormones and gradually cannot get away from them. Although doctors know the side effects of hormones are great, they can’t help it, and many patients can’t manage much pain. The safest and most effective hormone reducer is methotrexate. Many rheumatologists advocate methotrexate as the drug of choice for the treatment of rheumatoid arthritis. And methotrexate is very inexpensive. However, methotrexate is an anti-cancer drug and has potential toxicity, so it should be used under the guidance of a specialist and not blindly by yourself. In addition, the effect of some new drugs such as Eroval can also be achieved. There is no fixed pattern for the reduction of hormone dosage, but it should be reduced according to the type of disease, condition, amount of hormone, time of use and adverse drug reactions, etc. In rheumatoid arthritis, a small dose is generally used, and the dosage is gradually reduced in the process of the second-line drugs, such as 2.5mg orally, 3 times a day, and 2.5mg per month, and the hormone is withdrawn after several months. For rheumatic immune diseases that are difficult to control, such as systemic lupus erythematosus, adult sclerosis, and various systemic vasculitis, the dose is generally reduced slowly and for a long time, such as once every 7-10 days, each time by 10%; for diseases that are relatively easy to control, such as drug allergy, the dose is reduced quickly and for a short time, such as once every 3-5 days, each time by 20%.