Infections with Gram-positive cocci are mostly seen in skin infections, respiratory infections such as acute bronchitis and bacterial pneumonia, and also in purulent tonsillitis. For this type of infection, sensitive antibiotics are often used for effective anti-infection treatment, commonly used drugs such as penicillin, first generation cephalosporins such as cefazolin sodium pentahydrate, macrolides such as erythromycin, roxithromycin, azithromycin, etc. for effective anti-infection treatment. After three days of treatment, the patient’s condition will be evaluated to determine the effect of treatment, and the patient’s secretion will be taken for bacterial culture and drug sensitivity examination, and the results of drug sensitivity examination will provide the basis for the next treatment plan of anti-infection.