As the old saying goes, “every medicine has its poison”! Some medications can affect the development and quality of sperm and egg cells, which can affect a pregnant mother’s ability to conceive. Some drugs may cause abnormal fetal development, or even malformation or stillbirth. The metabolic cycle of drugs in the human body can be long or short. For the sake of the health of the upcoming baby, which drugs can and cannot be taken during the critical period of pregnancy preparation? First of all, it must be clear that our body has a certain ability to heal itself! For common colds and diarrhea, which are common minor ailments. The intake of foods rich in minerals, vitamins and high quality proteins, keeping a happy mood and getting enough sleep can strengthen the resistance of a pregnant mother and speed up her self-healing! However, when there is no way to heal ourselves, we need to use medication to help us heal. When using medication, pregnant mothers should follow the following three principles. Medication principle 1: Always follow your doctor’s instructions! When a pregnant mother is sick and sees her doctor, she should always state that she is preparing for pregnancy. When using over-the-counter medications, read the instructions, and if it is stated that “use with caution during pregnancy”, use it sparingly if you can, and do not use it if you can. When using prescription drugs, pregnant mothers should follow the doctor’s instructions, try to shorten the course of medication, and reduce or stop the dosage in time. You cannot stop the medication at your own discretion, which will affect the treatment effect. The second principle of medication use is to consider the effect on germ cells and fetus. If medication must be used, pregnant mothers should choose the drug that has the least impact on pregnancy and the fetus as much as possible. During the treatment phase of certain chronic diseases, pregnant mothers need to stop taking medication for a period of time or change their medication regimen according to their doctor’s advice before they can prepare for pregnancy. The third principle of medication is to be careful with health care products, charlatan prescriptions and ancestral secret recipes. During the preparation stage, except for folic acid or multivitamins for women in the perinatal period, pregnant mothers do not need to add additional health supplements to their healthy diet. The safety of prescriptions and recipes has not undergone rigorous clinical trials, and even the ingredients are sometimes kept secret, so you must be cautious! Finally, a word about what has to be said: immunizations. Certain infectious diseases such as rubella can increase the risk of miscarriage and fetal malformation after infection. Therefore, women who have not been vaccinated against these diseases are advised to be immunized against avoidable diseases before pregnancy. The recommended vaccinations include rubella, hepatitis B, hepatitis A, influenza, chickenpox, etc. It is generally recommended to get vaccinated 3 months before pregnancy. The doctor’s word is definitely “holy” on whether or not to use medication and what medication to use, so pregnant mothers should not take it upon themselves to blindly refuse medication or abuse it!