General hormones refer to glucocorticoids, which are extremely widely used clinically, with the following specific indications: First, primary and secondary hyperalgesia, requiring long-term replacement therapy with glucocorticoids, with the most clinical applications being prednisone and hydrocortisone. Second, autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, polymyositis dermatomyositis, etc., all need to be treated with glucocorticoids. Third, serious infections, glucocorticoids can be used to control symptoms and improve stress capacity. Fourth, all kinds of shock, like anaphylaxis, toxic shock, etc. can be treated with glucocorticoids for anti-shock treatment. Fifth, various allergic diseases, such as contact dermatitis and drug allergy, are also indications for glucocorticoids.