There are many reasons for difficulty in sleeping, as follows: First, physiological factors: that is, physiological insomnia, research has found that many people start to have insomnia when they reach the age of 45 or more, especially after the age of 60 or more, and some patients mainly show difficulty in falling asleep and relatively shallow sleep. In fact, it is because as we grow older, the brain’s regulation of sleep declines. For this situation, you can pass lifestyle interference and medication, as follows: 1. Lifestyle intervention: it is recommended to do relaxation training before bedtime and do more aerobic exercise during the day. 2. Medication: with eating some drugs, such as zopiclone and dezopiclone. Second, pathological factors: the most typical is anxiety, depression disorder, so that patients must use anti-anxiety, antidepressants, with the use of drugs to improve sleep, such as alprazolam, lorazepam, generally with the improvement of anxiety, depression symptoms, the patient’s sleep can also be relieved.