Redness and swelling of pimples under the nose that hurt when touched may be caused by folliculitis, sebaceous cysts, boils and other diseases, which can be treated by oral medication and application of medication. 1. Folliculitis: if the face often use poor quality cosmetics, or often appear sweaty phenomenon, may lead to the skin under the nose damaged, which leads to bacteria or fungi invasion into the hair follicles, so that the patient appears under the nose acne, redness, swelling, and pain when touching the phenomenon. You can apply mupirocin ointment, fusidic acid cream and other drugs to treat. 2. Sebaceous cysts: usually caused by sebaceous gland excretory duct obstruction, excessive content in the sebaceous gland under the nose to form a cystic swelling, if the secondary infection will appear pain. It can be treated with topical application of gold cream or oral medication such as amoxicillin potassium clavulanate tablets. After the inflammation subsides, the cyst can be removed surgically. 3. Boils: may be caused by not paying attention to personal hygiene, or often scratching under the nose, after the disease will lead to lesions appearing in the red, painful nodules, which will cause pimples under the nose, redness, swelling, and pain when touched. You can take levofloxacin hydrochloride tablets, roxithromycin dispersible tablets and other drugs to treat it. The long acne under the nose, redness, swelling and pain when touched may also be caused by other reasons, the patient needs to consult a doctor in time to find out the cause, symptomatic treatment, the above drugs need to be used in accordance with the doctor’s instructions.