The rough surface of cardia bulge may be gastritis, or gastric polyp, or gastric cancer, which needs pathologic examination for further clarification and targeted treatment. 1. If it is caused by inflammatory stimulation, acid-suppressing drugs such as omeprazole should be taken orally under doctor’s guidance. If Helicobacter pylori is positive, it is recommended to give quadruple therapy to clear HP, such as omeprazole, bismuth potassium citrate, amoxicillin and clarithromycin. 2. If gastric polyps are present, microscopic resection of polyps is recommended, with regular review of gastroscopy. 3. If there is malignant transformation, it can be treated by surgery and radiotherapy, so as to improve the effect of the disease. In addition, junk food should be avoided in daily life. Eat fluffy and easy to digest food, three meals regularly, regular and quantitative, the diet should be light, less spicy, low salt, low sugar, into the warm food, avoid hot, avoid cold, avoid smoking, avoid alcohol, avoid strong tea, avoid stimulating food, avoid excessively rough food. Keep a happy mood, avoid tension and anxiety. Pay attention to hygiene, avoid infection of Helicobacter pylori. Cardia bulge surface roughness, etiology is more, it is recommended to consult the doctor as soon as possible, the pathology examination, targeted treatment.