Two arm pain is common in the following reasons: First, double upper limb muscle strain, the patient recently overworked, double upper limb muscle severe strain, the patient can have muscle soreness, pain symptoms, accompanied by upper limb weakness. Second, cervical spondylosis, cervical disc herniation, can compress the bilateral nerve roots, causing bilateral upper extremity radiating pain symptoms. The patient’s pain is usually more intense, and will be accompanied by cervical pain and activity limitation, through the MRI examination, can confirm the diagnosis of cervical spondylosis caused by upper limb pain. Symmetrical pain in the upper limbs should be consulted in time, and the etiology can be determined through physical examination and imaging examination, and finally the treatment can be based on the etiology, so that the pain symptoms of both upper limbs can be relieved satisfactorily. Patients should also pay attention to avoid overwork and protect the cervical spine to avoid double upper extremity pain symptoms.