Melatonin is mainly used to treat people with insomnia, but melatonin should not be taken for a long time. Long-term use of melatonin can lead to drug dependence and resistance, so it is important to limit the daily dose of melatonin. Long-term use of melatonin can also lead to endocrine disorders, affecting the secretion of hormones, which can have a negative impact on the body and cause many adverse symptoms. If melatonin is taken during pregnancy preparation, it can also affect the effect of pregnancy preparation, and long-term use of melatonin can cause infertility. Therefore, people taking melatonin need to pay attention to, especially the more sensitive people, need to pay attention to taking melatonin at the same time can not ingest spicy, spicy, frozen and other stimulating food, in order to avoid causing intestinal discomfort, as well as the appearance and drug effects of the conflict.