There may be side effects such as allergy, fever, fatigue, cough, headache, diarrhea, local pain and hard nodules after vaccination. 1. Localized muscle pain and hardness will appear after vaccination, this symptom is the most common side effect, there is no need to panic and do not need to do any treatment, usually after 2~3 days, it will recover by itself. 2. After vaccination, some patients may have skin rash or itching symptoms, indicating that the patient is allergic to the vaccine, and in severe cases, laryngeal edema and respiratory difficulties may occur, which should be promptly told to the doctor at the vaccination site. 3. Some patients may develop flu-like symptoms, such as fever, malaise, cough and headache, which may be related to the production of immunity in the patient’s body and require symptomatic treatment in severe cases. It is normal to experience mild side effects after vaccination due to the different physique of each individual. After vaccination, it is important to keep the local skin clean and dry, avoid irritation and do not scratch. The general side effects of the vaccine will disappear in 2~3 days. If the symptoms worsen, you should seek medical advice.