High urine leukocytes in men may be related to pyelonephritis, cystitis, prostatitis and other diseases. 1. Pyelonephritis: It is mainly caused by pathogenic microorganisms invading the renal pelvis and renal parenchyma, which will increase the white blood cells in male urine. For this condition, drugs can be used for treatment, and the common ones are fluoroquinolone antibiotics, penicillin antibiotics, cephalosporin antibiotics and so on. 2. Cystitis: mainly manifested as frequent urination, urinary urgency, urinary pain (urinary tract irritation sign). Pathogenic bacteria are mostly Escherichia coli. Combined with urine culture and drug sensitivity test, oral levofloxacin, cephalosporin and other drugs to control inflammation as prescribed by the doctor. 3. Acute bacterial prostatitis: In life, pathogenic infections can lead to acute bacterial prostatitis, the onset of urine leukocytosis. This kind of disease is mainly treated with drugs, such as levofloxacin. Secondly, in life, it is necessary to strengthen self-care. Men with elevated urine leukocytes, accompanied by uncomfortable symptoms, should seek medical treatment as soon as possible, do not delay the condition.