Suddenly, everything you eat is bitter, which is related to bile reflux gastritis, cholecystitis, and mouth ulcers. The appearance of bile reflux gastritis is related to gastrointestinal dysfunction. When the pressure in the intestine is too high, it is difficult to drain food from the stomach into the intestine, and even the contents of the duodenum can reflux into the stomach. When the contents enter the esophagus, it will not only affect the esophageal mucosa, but also cause bitterness in the mouth due to the reflux of bile. During the period of cholecystitis, patients will not only suffer from severe pain in the abdomen and indigestion, but also the bile will enter the blood circulation due to poor drainage, which will cause bitterness in the mouth. This is directly related to mouth ulcers, which can cause abnormal taste nerve function due to inflammatory stimulation, so any food will feel more bitter when eating.