Lymphoma is also a systemic lesion and belongs to the malignant tumors of hematopoietic system. Generally speaking, if women find unexplained enlarged lymph nodes in armpits, they should be alert to the possibility of lymphoma, also known as malignant lymphoma. The diagnosis can be confirmed by doing pathology through surgery. Generally speaking, there are no obvious symptoms and the main manifestation is painless enlarged lymph nodes. With the development of the disease, there may be systemic manifestations in the middle or late stage, such as fever, fatigue, weight loss, and pain in the axillary mass. After lymphoma is diagnosed, immunohistochemistry is mainly done to determine the specific type. The treatment plan mainly adopts chemotherapy as the mainstay, and can be combined with targeted drugs and other treatments, which can improve the efficacy.