Eczema on hands need to take comprehensive treatment to completely remove, including general treatment, local medication, systemic medication and so on. 1. General treatment: patients need to avoid hand contact with external irritants, such as hot water, contact with allergens, local scratching, contact with irritating substances, etc., and do a good job of hand care. 2. Topical medication: you can use Denadyl cream, hydrocortisone butyrate ointment, tacrolimus ointment and other drugs for topical application, so as to alleviate the phenomenon of eczema on the hands. 3. Systemic medication: Oral antihistamine medication can be taken under the guidance of a doctor, such as loratadine, etc.; if eczema on the hands is more serious, it can be combined with immunosuppressants, such as methotrexate, cyclosporine, etc., if necessary. Eczema on the hands need comprehensive treatment, it is recommended that the hospital dermatology consultation, the above drugs should be used under the guidance of a doctor, can not be used indiscriminately, so as not to lead to adverse consequences.