In general, the normal value of prolactin in adolescent females should be (436.00±3.76) mU/L. As a polypeptide hormone, prolactin, also known as prolactin, is one of the hormones secreted by the pituitary gland. For adolescent girls, the normal girl’s prolactin value should be around (436.00±3.76) mU/L. If there is elevated prolactin, it can be called hyperprolactinemia in medical aspect, which belongs to the dysfunctional disorder of hypothalamus pituitary gonadal axis, and may cause pubertal girls to have reduced menstrual flow, scanty hair, amenorrhea, lactation and so on. Therefore, when adolescent girls have the above symptoms, they should be highly suspicious of the possibility of hyperprolactinemia, and should cooperate with the doctor to do further examination to determine the cause, and then do targeted treatment and therapy.