Broadly speaking, ulcers throughout the gastrointestinal tract are called ulcer disease, however, in clinical practice it often refers mainly to the loss of restricted tissue caused by the digestion (self-digestion) of the gastric and duodenal mucosa and its deeper tissues by the gastric digestive juices. Ulcer disease is divided into two main categories: 1. primary (idiopathic) ulcers, mostly chronic, mainly duodenal ulcers; 2. secondary (stress) ulcers, mostly acute ulcers, mainly in the stomach, more likely to occur in newborns and infants, often with known primary diseases, such as hypoxia, asphyxia, severe pulmonary disorders, sepsis, central nervous system disorders, burns, severe trauma, long-term application of hormones and non steroidal anti-inflammatory drugs (NSAIDs), misuse of corrosive agents, etc. Clinically, peptic ulcers mostly refer to primary ulcers, which are classified as gastric ulcers, duodenal ulcers, and compound ulcers (referring to ulcers in both the stomach and duodenum) according to the site of origin.