Uremia is the end stage of various chronic kidney diseases, and the causes of uremia mainly include primary, secondary, and hereditary kidney diseases. Primary kidney diseases such as glomerulonephritis, tubulointerstitial disease, renal vascular disease, etc., and secondary kidney diseases such as diabetes-induced nephropathy, hypertension-induced nephropathy, etc., as well as hereditary nephritis, polycystic kidney and so on, may cause renal failure, and if they are not treated timely and effectively, and develop into the end stage of renal failure, they will eventually lead to the occurrence of uremia. There may be other causes of uremia, so patients are advised to go to regular hospitals in time for consultation and standardized treatment under the guidance of doctors.