The pain in the front of the calf when running may be caused by the pain of the tibial tuberosity due to sports injury, or it may be caused by the pain of the myofascial strain around the joints and bones or the pain caused by the muscle attachment points, and this kind of pain is mostly seen in the long time and large amount of sports or improper sports caused by the sports injury. If there is pain in the front of the calf when running, we should appropriately reduce the amount of exercise or change the appropriate sports equipment, especially shoes, to avoid aggravating sports injuries, resulting in irreversible skeletal myofascial injuries, seriously affecting the activities. Some patients who have been exercising excessively for a long time should also pay attention to fatigue fractures.