Elevated renin is generally considered to be due to renal insufficiency, renal artery stenosis, renal tumors and other pathological factors, as well as nervousness, anxiety and other psychiatric factors, and can generally be treated by taking medications, surgery and emotional regulation. Renin is a protein hydrolyzing enzyme released by glomerular paraglomerular apparatus, which is a component of the renin-angiotensin-aldosterone system and participates in the regulation of blood pressure in the human body. 1.Pathologic factors: (1) Renal insufficiency: if you suffer from chronic renal failure, chronic glomerulonephritis, nephrotic syndrome, diabetic nephropathy and other diseases, it can lead to renal insufficiency, which can cause the creatinine level to rise, resulting in the elevation of renin, at this time, it can be treated by taking angiotensin-converting enzyme inhibitor such as captopril or angiotensin II receptor antagonist such as valsartan and other drugs. (2) Renal artery stenosis: when renal artery stenosis occurs, it will make sympathetic nerves excited, causing increased renin release, which can be treated by taking antiplatelet aggregation drugs such as aspirin, lipid regulating and stabilizing drugs such as atorvastatin calcium tablets and other drugs. (3) Kidney tumor: If you have kidney tumor, pheochromocytoma and other diseases, it will also cause the increase of renin level, and if necessary, you can have the tumor resection surgery for treatment. (2) Physiological factors: mental tension and anxiety can also cause elevated renin secretion, which can be treated by resting and psychological counseling to regulate emotions. If you find that renin is elevated, you should relieve your mood and suggest to consult a doctor in time to find out the cause and follow the doctor’s instructions.