A pins and needles sensation in the skin may be caused by central nerve compression, which is a result of osteophytes or herniated discs. It may also be necrosis or inflammation of peripheral nerves caused by diabetes. Clinically, compressive lesions in the cervical, thoracic, and lumbar spine can lead to the manifestation of pins and needles sensation in the skin of the corresponding areas. Compression of the cervical spinal nerve by intervertebral discs can cause pins and needles sensation at the end of the fingers; compression of the lumbar spinal nerve by lumbar intervertebral discs can cause pins and needles sensation in the skin of the lower limbs, which can only be relieved by surgical or physiotherapeutic measures to relieve the compression of the nerves. Diabetes can cause necrosis or inflammation of peripheral nerves, which can also cause pins and needles, and other peripheral neuritis can also have a similar situation, and only by treating the primary symptoms can the symptoms be improved. It is recommended that the patient go to the hospital in time to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.