The following possibilities should be considered when stomach pain occurs on the 52nd day of pregnancy: First, pregnancy-related stomach pain, such as when the patient has a preterm miscarriage or ectopic pregnancy, requires dynamic observation of blood chorionic gonadotropin, progesterone and changes in color ultrasound to determine the specific cause. Secondly, gynecological related diseases unrelated to pregnancy should be considered, such as cervical lesions, inflammatory vaginal lesions, pelvic infections, etc., which need to be differentially diagnosed by gynecological examination, ultrasound, routine blood tests and other related tests. Thirdly, we should consider abdominal pain caused by other pathologies unrelated to pregnancy and gynecology, such as enteritis or urinary tract infection, which are mostly accompanied by abnormal stools, nausea, vomiting or frequent, urgent and painful urination, and other clinical manifestations, which need to be identified by relevant examinations according to the situation.