The pain in the extremities may be caused by gout disease. If the blood uric acid value is significantly high, it means that the pain is caused by gout attack. It may also be caused by rheumatoid arthritis, as rheumatoid disease can also cause pain in different joints during an attack and can lead to wandering pain in the extremities. It is recommended that patients must go to the hospital for detailed examination, such as local X-ray examination, as well as blood tests for rheumatic complete set, which can effectively clarify the diagnosis. When it is clear that rheumatoid arthritis is the cause, it is recommended that the patient’s affected limbs be protected to effectively avoid pain, and can take aminotrimadol tablets and ibuprofen extended-release capsules, which can effectively control local inflammation and pain symptoms.