Most of the kidney diseases are related to autoimmune dysfunction, and hormones have powerful anti-inflammatory and immune-regulating effects, which can treat many types of kidney diseases, such as for mesangial proliferative glomerulonephritis, membranous nephritis, nephrotic syndrome and other diseases, which need to be treated with hormones. In the process of medication, it is also necessary to pay attention to the drug-related side effects, such as long-term application of hormones may bring osteoporosis, immune deficiency, infection, steroid diabetes, femoral head necrosis and other related complications, need to pay attention to prevention, regular follow-up in the hospital for review, monitoring of renal function, urinalysis, urine protein quantitative and other indicators, to assess the recovery of renal disease, and then according to the results of the relevant tests to adjust the treatment program.