The role and efficacy of aspirin is to inhibit platelet aggregation, antipyretic and analgesic, clinically used in ischemic cardiovascular and cerebrovascular diseases, rheumatoid arthritis and other diseases treatment. Aspirin has the effect of inhibiting platelet aggregation, small dose effect is more obvious, at the same time has the efficacy of antipyretic and analgesic, clinically can be used for ischemic cardiovascular and cerebrovascular diseases, a variety of pain, rheumatoid arthritis, and other diseases, different diseases to choose a different dose. Aspirin’s main role is to inhibit the efficacy of cyclooxygenase, reduce the generation of thromboxane A2 in the body, the adverse effects of the drug are stomach pain, stomach bloating, nausea, bleeding of the skin mucous membranes, bleeding in the urinary tract, gastrointestinal bleeding, cerebral hemorrhage, etc. Allergy to drug components, aspirin-related asthma, active ulcers, active bleeding, blood disorders, etc., is prohibited for patients. Clinical selection of aspirin for treatment should be under the guidance of physicians to choose the appropriate indications.