The etiology of pemphigus has not been fully clarified, and it is currently thought to be an autoimmune disease whose pathogenesis is related to the binding of autoantibodies to epithelial cell surface antigens resulting in the loosening of the spinous layer. Pemphigus is a chronic, recurrent autoimmune disease, and most patients have anti-spinocyte-specific antibodies in their serum. The treatment of pemphigus is aimed at controlling the occurrence of new lesions and preventing secondary infections, and glucocorticoids are the drugs of choice for treatment. With regular treatment, most patients can have a better prognosis. Patients with pemphigus need to go to the hospital as soon as possible, and the doctor will formulate an individualized diagnosis and treatment plan according to the specific condition, so as not to delay the condition.