Twenty years of urethritis can be caused by improper care, incorrect medication or other primary diseases, as long as the reasonable treatment, most of them can be cured, including general treatment, drug treatment, treatment of other primary diseases. 1. General treatment: daily care should be strengthened, keep the lower body clean, wash the underwear diligently, and do not have unclean sex, eat less stimulating food, do not drink alcohol and smoking. 2. Drug treatment: you should go to the doctor for a detailed examination to clarify the type of causative bacteria, and then use sensitive antibacterial drugs for treatment, such as azithromycin, levofloxacin, etc., and be sure to use the drug in full dosage and full course of treatment, and after the disappearance of the symptom, you should also go to the doctor for a review, to clarify the causative bacteria whether it has been completely cleared up. 3. Treatment of other primary diseases: the presence of other primary diseases, such as urethral stenosis, may repeatedly induce urethritis, should be directed at urethral stenosis treatment, such as urethral dilatation surgery, to eliminate the cause of the disease. In the treatment period, must follow the doctor’s instructions, reasonable use of drugs for treatment, not self-medication, to avoid affecting the recovery.