Gout is caused by excessive accumulation of uric acid in the body. Young women who are not yet menopausal rarely have gout attacks with increased uric acid under the protective effect of estrogen. For example, we should first investigate whether there are kidney diseases, such as chronic renal insufficiency, etc.; or whether there are immune diseases, such as systemic lupus erythematosus, which leads to kidney impairment and decreased kidney function, thus causing an increase in uric acid; or whether there are certain drugs that may affect uric acid excretion, thus causing an increase in uric acid gout attack. Gout attacks may occur in menopausal women who lack the protection of estrogen, usually due to an impairment in the body’s metabolism of uric acid. Secondly, the increase of uric acid is also related to diet, such as drinking alcohol or eating high purine food, so it is necessary to further improve the relevant examination, such as kidney function, kidney ultrasound, immune function related examination, to clarify whether there is a kidney disease and immune system disease, and to screen the current drugs to see whether the side effects of drugs have affected the excretion of uric acid, and actively find out the cause of the disease. After that, we should use drugs to treat the disease.