Postoperative oozing after open lumbar spine surgery may be caused by subcutaneous fat liquefaction, local inflammation and infection, cerebrospinal fluid leakage, etc. It can be treated in the hospital. When there is more fat at the incision and electrosurgery is used, it is easy to lead to aseptic necrosis of subcutaneous tissues, which will easily form fat ooze and affect wound healing after the operation, and if it is not cleaned up in time, it will lead to local inflammation and infection in the long run. If the patient has headache symptoms, sinus, middle ear and other parts of the fluid flow sensation, may also be cerebrospinal fluid leakage. If it is fat leakage, patients are advised to change the medication on time, and when the situation is not good, clean-up suture can be taken. If it is due to infection, anti-inflammatory treatment is needed. In case of cerebrospinal fluid leakage, bed rest is recommended. If necessary, a drain should be placed or lumbar pool drainage should be performed to reduce the pressure within the cerebrospinal fluid. If the patient’s physical condition is not good, please seek medical advice and cooperate with the doctor.