Cranial defects not only damage the patient’s image, but also pose a serious threat to the patient’s health and safety. Individual patients clinically experience memory loss after debridement. This condition is mainly a manifestation of retrograde amnesia due to damage to the brain functional areas associated with memory after the patient’s injury, and the recovery of some neurological functions can be promoted through cranial repair. When the neurological function is well restored, it helps the patient to recover memory as early as possible. In addition, skull repair can also restore the normal shape of the patient’s head and increase the safety of the patient. With the protection of the skull, it can effectively avoid the re-injury of the brain tissue and the occurrence of various adverse reactions. The choice of repair material when doing skull repair is also an important factor to determine the postoperative effect of patients. Good material not only can achieve good repair effect, but also can effectively avoid some postoperative discomfort. For example, many patients choose to use titanium mesh as the repair material, and there are problems such as rejection and infection after surgery. Currently, we use polyether ether ketone peek material as the skull repair implant material, carry out polyether ether ketone PEEK skull repair plastic surgery, and further summarize and study hundreds of completed cases to improve and upgrade the technology. For example, the unique peek material thickness and mesh aperture design pioneered and the unique intraoperative tissue separation and repositioning technique can increase blood flow, effectively avoid temporal muscle atrophy, and ensure the activity of each tissue. Appropriate treatment of aesthetic factors, such as subcutaneous freeing, flap transfer, myofascial flap with tip transfer, and brow arch shaping, is also carried out, and the postoperative cosmetic results are widely favored by the public.