1. Patient Meng, male, 60 years old, Jinan City Acrobatic Troupe. Diabetes mellitus for more than 10 years, urine protein ++++, diagnosed as diabetic nephropathy. Given a low salt and low protein diet, insulin plus acarbose to control blood sugar, Bailing capsule, nephritis rehabilitation tablets to supplement the kidney and lower protein, intermittently taking Chinese medicine to regulate, the current urine protein negative, occasionally appear urine protein +. Note: The current medical opinion is that urine protein appears in the urine routine, which belongs to stage 4 diabetic nephropathy and belongs to the irreversible stage, and the condition keeps progressing forward. This patient’s timely medication, especially good compliance and strict adherence to medical advice, is the key to achieving results. 2. Patient Li, female, 58 years old, diabetic for 5 years, urine protein ++, blood biochemistry: creatinine, urea nitrogen elevated. Admitted to hospital. He was given insulin to control blood glucose, nephritis rehabilitation tablets to protect kidney, renkang injection intravenous drip, traditional Chinese medicine Shengveisan and Liuwei Dihuang Tang plus or minus, a total of 28 days in hospital, at the time of discharge, urine protein negative, creatinine normal, only elevated microalbumin, asked to review outpatient. At the time of discharge, urine protein was negative, creatinine was normal, and only trace protein was elevated. Note: This patient is still taking Chinese medicine, good blood sugar, no obvious discomfort, continue to consolidate the effect of treatment. 3. Patient Zhang, 78 years old, retired, diabetic for 8 years, not systematically treated, with high blood glucose and positive urine protein, so he was admitted to the hospital. After admission, he was given insulin to lower glucose, a low-protein diet, the Chinese medicine Jisheng Renqi Tang plus reduction, and other symptomatic treatment; he was hospitalized for more than 20 days and was discharged with improvement. After discharge, urine protein disappeared, microprotein was high, and he continued to take Chinese medicine as an outpatient. Note: This patient is still taking Chinese medicine in outpatient clinic, one dose in two days, which is intended to consolidate the efficacy of treatment. Conclusion: Diabetic nephropathy is one of the serious complications of diabetes mellitus, and its danger lies in uremia, which requires dialysis treatment and brings a very big economic burden and psychological burden to families. Therefore, early intervention and early treatment are crucial to prevent the development of uremia. It is very wise for us to advance the point of treatment, early intervention and early treatment, among which, the combination of Chinese and Western medicine is very important.