In the acute stage of cerebral infarction, patients do not sleep at night and toss and turn will easily lead to the aggravation of the progress of cerebral infarction, and rest is very beneficial to the recovery of the patient’s disease. Brain infarction patients who do not sleep at night may be considered because the disease has led to changes in the patient’s psychological state, anxiety and depression, for this situation, the main thing is to give the patient psychological guidance, while giving the patient some drugs to improve the mood, commonly used are escitalopram oxalate, Dextran to improve the patient’s mood. If the patient has mental changes due to the site of cerebral infarction, tossing and turning at night without sleeping, the main thing is to treat cerebrovascular disease, improve the blood supply to the brain, give the patient sedation and sleep, so that the patient can sleep quietly, you can give the patient intramuscular injection diazepam.