Chest tightness, shortness of breath and sleeplessness may be related to cardiac insufficiency, and it is recommended to give regular anti-heart failure treatment and medication to assist sleep. Chest tightness, shortness of breath may also be acute myocardial ischemic attack, it is recommended to give blood pressure, heart rate monitoring, to clarify the status of blood pressure, if necessary, give nitrate drugs, such as nitroglycerin tablets, isosorbide nitrate tablets, or proprietary Chinese medicine, such as quick-acting heart pill, compound danshen drip pill and so on symptomatic treatment, and it is recommended that the oxygen inhalation to improve the shortness of breath symptoms. After the symptoms are relieved, sleep-assisting drugs can be given, such as benzodiazepine-type sleep-assisting drugs to assist sleep. Chest tightness and shortness of breath are also common in patients with coronary artery disease, and it is recommended to give regular secondary prevention of coronary artery disease with medication, and surgery if necessary. Nighttime can be supplemented with sleep-assisting related drugs, symptomatic treatment.