The significance of pH 4.6 represents is usually related to the specimen tested by the patient, such as the normal value of urine pH is 4.6-8.0, with an average value of 6.0. pH 4.6 means that the overall urine is acidic, which may be affected by a variety of factors, such as bad dietary habits, kidney damage, respiratory system diseases, etc. 1, bad dietary habits: the human body consumes too much metabolic substances that will produce a lot of acid after metabolism Food, such as animal offal, fish skin, spinach, purple kale, cola, coffee, strong tea, etc., will produce tannic acid, uric acid or phosphoric acid and other metabolic substances, resulting in the overall acidity of urine acidity, and even the risk of urinary stones; 2, kidney damage: may be the kidneys themselves have functional damage, for some patients with diabetes or long-term poor control of hypertension, kidney function can be affected to a certain extent. The kidney function can be affected. This part of the patient’s urine pH is generally difficult to control in the normal range, urine acidity suggests that the patient’s kidney function is not good, more attention should be paid to the treatment and control of the original disease; 3, respiratory system diseases: such as chronic respiratory failure, chronic obstructive pulmonary disease, pulmonary fibrosis, etc., will lead to abnormal blood pH, blood pH abnormalities will also affect the urine pH, so that the phenomenon of urine acidity, then it is Targeted treatment is needed for respiratory system diseases; 4. Other conditions: such as fever, gout, cardiovascular system diseases, taking vitamin C, ammonium chloride and other drugs, may also lead to changes in urine pH. A single pH measurement usually has little clinical significance. For patients with abnormal changes in pH, in addition to observing the presence or absence of clinical symptoms, a more comprehensive and routine physical examination is needed to make a comprehensive and specific diagnosis.