There is no clear evidence that mixing neocoronavirus vaccines is more effective. According to the guidance in the Technical Guidelines for Neocoronavirus Vaccination, 1st Edition, it is recommended that people without contraindications to vaccination should receive neocoronavirus vaccination to prevent neocoronavirus infection, and it is also recommended that the same vaccine species should be used to complete neocoronavirus vaccination. If, in the course of vaccination, special circumstances such as off-site vaccination or change of vaccine supply type occur, the same type of vaccine produced by other manufacturers should be used to complete the continuation of vaccination as far as possible. The guideline does not recommend mixing the Neocoronavirus vaccines, and there is no clear administrative medical evidence of their effectiveness, so it is recommended to follow the guideline’s vaccination recommendations.