Itchy skin is usually a symptom of fungal dermatosis, eczema, scabies and pruritus, and requires a prompt visit to the dermatology department of the hospital for a definitive diagnosis and medication according to the doctor’s instructions. There is no such thing as a quick fix for itchiness due to the differences in individual constitution and condition. Itchy skin treatment needs to be based on different causes of the use of drugs, mainly including antifungal drugs, antihistamines, glucocorticoid drugs and so on. Fungal skin diseases include ringworm, jock itch, tinea versicolor and so on. Treatment can be oral antifungal drugs such as terbinafine hydrochloride tablets, fluconazole tablets and so on. Topical antifungal drugs such as miconazole, ketoconazole, bifonazole, terbinafine. Eczema is caused by a variety of factors inside and outside the body, the treatment is based on antihistamines, oral antihistamines such as ebastine tablets, loratadine tablets and so on. Topical glucocorticoid creams such as mometasone furoate ointment, hydrocortisone butyrate cream. Scabies is caused by parasitic scabies infection, daytime itching light night aggravation, can be taken orally before bedtime the first generation of antihistamines to stop itching and promote sleep, such as chlorpheniramine maleate tablets, phenylephrine tablets, etc., it is best to cooperate with the sulfur ointment, benzyl benzyl acid ester emulsion and other insecticidal and anti-itching medications for topical use. Pruritus is mostly caused by dry skin, need to control the frequency of bathing, bathing water temperature to maintain appropriate, apply moisturizing moisturizing cream after bathing and so on. There may be other reasons for itchy skin, it is recommended to go to the hospital in a timely manner, to identify the cause, symptomatic treatment, drugs need to be used in accordance with medical advice.