Regional progesterone tablets are known as Daphne, a drug that is often used in obstetrics and gynecology. Its allergic reactions are manifested in various systems, such as in the blood and lymphatic system, in the immune system, nervous system and digestive and hepatobiliary systems, as well as in the skin and mental system, after taking regional progesterone tablets. These allergic reactions can specifically manifest themselves in the form of migraine, nausea, vomiting, vertigo, impaired liver function, drowsiness and skin allergies, such as atopic dermatitis, as well as itchy skin dermatitis and urticaria. Other patients can experience breast tenderness after taking this drug. If these allergic reaction symptoms are mild, it is possible to continue taking the drug, but if these allergic reaction symptoms are severe, it is recommended to stop taking the drug.